Overview
Lyvelsa 20mg Tablet is used in adults for managing chronic kidney disease (CKD) associated with type 2 diabetes. It works by blocking specific hormones in the body, helping to protect kidney function and lowering the risk of heart-related problems such as heart attacks and heart failure.
How to Take
This tablet can be taken with or without food. Your doctor will determine the appropriate dose and treatment duration. During therapy, your doctor may monitor your blood pressure, heart rate, ECG, kidney function (eGFR), urine albumin-to-creatinine ratio (UACR), and potassium levels until your condition stabilizes. Continue all other prescribed medications for your long-term treatment alongside this therapy.
Possible Side Effects
Some people may experience elevated potassium levels, low blood pressure, or decreased sodium levels. If these occur, inform your doctor, who may adjust the dosage or recommend an alternative medication.
Precautions
Lyvelsa 20mg Tablet may not be suitable for everyone. Inform your doctor if you have kidney or liver issues or are taking other medicines. Women who are pregnant or breastfeeding should consult their healthcare provider before starting this medication.
Uses
- Management of chronic kidney disease
Benefits
Lyvelsa 20mg Tablet helps slow the progression of kidney damage in adults with CKD linked to type 2 diabetes. It lowers the risk of advancing to end-stage kidney disease, reduces heart-related complications, decreases hospitalization due to heart failure, and may lower the risk of cardiovascular-related death, supporting overall kidney and heart health.
Common Side Effects
- Raised potassium levels in blood
- Low blood pressure (hypotension)
- Reduced sodium levels in blood
How to Use
Take the tablet exactly as prescribed. Swallow it whole without chewing, crushing, or breaking. While it can be taken with or without food, it is preferable to take it at the same time each day.
Mechanism of Action
Lyvelsa 20mg Tablet is a selective, nonsteroidal mineralocorticoid receptor antagonist. By preventing overactivation of this receptor, it protects the kidneys, heart, and blood vessels from hormone-induced damage, helping maintain organ health.
Safety Guidelines
- Alcohol: Consult your doctor before consuming alcohol.
- Pregnancy: Speak with your doctor. Animal studies suggest potential risks; benefits must outweigh harm.
- Breastfeeding: Use caution. Avoid breastfeeding until the medicine has cleared from your system.
- Driving: Effects on driving are unknown. Avoid driving if you feel impaired.
- Kidney and Liver Conditions: Safe if prescribed. No dose adjustments are usually required.
Missed Dose Instructions
If a dose is missed, take it as soon as possible. If the next dose is near, skip the missed one and continue your regular schedule. Do not double the dose.





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