Product Description
Lupisit GM 50mg/1mg/1000mg Tablet is a combination medicine containing Glimepiride (1mg), Metformin (1000mg), and Sitagliptin (50mg). It is prescribed for the management of type 2 diabetes mellitus when single or dual therapy is not enough. The three medicines work together by improving insulin secretion, reducing sugar production in the liver, and helping the body use insulin more effectively.

Benefits
• Provides strong blood sugar control in type 2 diabetes
• Glimepiride stimulates the pancreas to release more insulin
• Metformin reduces liver glucose production and improves insulin sensitivity
• Sitagliptin enhances the body’s natural insulin response after meals
• Helps reduce long-term complications of diabetes like kidney, nerve, and eye problems

Side Effects
• Low blood sugar (hypoglycemia) especially if meals are skipped
• Stomach upset, nausea, diarrhea, or abdominal discomfort
• Headache, dizziness, or tiredness may be experienced
• Rarely, allergic skin reactions or pancreatitis may occur
• Lactic acidosis is a rare but serious side effect linked to metformin

How to Use
• Take exactly as prescribed by the doctor
• Swallow whole with water, preferably with meals to reduce stomach upset
• Try to take at the same time every day for consistent sugar control
• Do not stop the medicine suddenly without medical advice

What to Avoid
• Avoid alcohol as it increases the risk of low sugar and lactic acidosis
• Do not skip meals, as it may trigger hypoglycemia
• Avoid taking more than the prescribed dose
• Not suitable for type 1 diabetes or diabetic ketoacidosis

Precautions
• Inform your doctor if you have kidney, liver, or heart problems before starting
• Regular monitoring of blood sugar, kidney function, and liver enzymes may be needed
• Elderly patients should take with caution due to higher risk of low blood sugar
• Pregnant or breastfeeding women should use only if prescribed by the doctor
• Seek urgent medical help if you experience severe weakness, persistent vomiting, abdominal pain, or yellowing of skin/eyes