Overview

Duopil 2/500 Tablet PR is an oral medication used for managing type 2 diabetes in adults. It combines two active components that help lower blood sugar levels and support overall glucose control. Maintaining healthy blood sugar levels with this medicine can help reduce the risk of long-term complications associated with diabetes.

Dosage and Administration

This medicine should be taken with meals to reduce the risk of stomach upset. For optimal results, it is recommended to take it at the same time every day. The exact dose is determined by your doctor based on your blood sugar readings and how your body responds to the treatment.

Even if you feel well or your blood sugar appears normal, you should continue taking this medicine. Stopping treatment without guidance from your doctor can cause sugar levels to rise, increasing the risk of complications such as kidney problems, vision damage, nerve damage, or other serious health issues. This medicine is most effective when used alongside a balanced diet, regular physical activity, and proper weight management.

Common Side Effects

The most frequently reported side effect is low blood sugar (hypoglycemia). Warning signs of low blood sugar may include sweating, dizziness, headache, trembling, or confusion. Eating regular meals and having a fast-acting sugar source such as fruit juice or candy available can help prevent or manage hypoglycemia. Alcohol consumption may increase the risk of low blood sugar and should be avoided.

Other side effects may include nausea, diarrhea, stomach discomfort, headache, changes in taste, or mild respiratory infections. Some individuals may experience weight gain while taking this medicine. Most side effects are mild and temporary, and they usually resolve as the body adapts.

Who Should Avoid This Medicine

Duopil 2/500 Tablet PR is not suitable for people with type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver disorders. Patients with a history of heart disease should inform their doctor before starting treatment. Pregnant or breastfeeding women must seek medical advice prior to using this medicine. Regular monitoring of blood sugar, liver function, and kidney function may be recommended during treatment.

Uses

This medicine is prescribed to control blood glucose in adults with type 2 diabetes mellitus.

How It Works

Duopil 2/500 Tablet PR contains two active agents: Glimepiride and Metformin. Glimepiride stimulates the pancreas to produce more insulin, helping reduce blood sugar levels. Metformin decreases sugar production in the liver, slows absorption of sugar from the intestines, and improves the body’s response to insulin. Together, they provide effective control of blood glucose levels.

Precautions and Safety

Alcohol consumption should be avoided while using this medicine. Pregnant or breastfeeding women should consult their doctor before use. Blood sugar fluctuations can affect your ability to drive or operate machinery, so caution is advised if you experience symptoms such as dizziness or weakness. Dose adjustments may be required for patients with kidney or liver conditions, and regular monitoring is recommended.

Missed Dose Instructions

If a dose is missed, take it as soon as possible. If it is almost time for the next scheduled dose, skip the missed one and continue with the regular dosing schedule. Do not take a double dose to make up for a missed one.