Sitaglo MP 500 Tablet SR is a combination medicine prescribed for the treatment of type 2 diabetes mellitus. It helps control blood sugar levels when diet, exercise, and single therapy are not sufficient. By maintaining healthy glucose levels, it reduces the risk of long-term diabetes complications such as kidney damage, vision loss, nerve problems, heart attack, and stroke.

This tablet is usually recommended when dual therapy is required. Your doctor will decide the dose depending on your blood sugar readings, overall health, and other medicines you may be using. Taking it with food helps prevent stomach upset.

For best results, take it regularly at the same time each day and continue following a proper diet and exercise plan. Do not stop the medicine unless advised by your doctor.

Uses of Sitaglo MP 500 Tablet SR

Management of type 2 diabetes mellitus

Benefits of Sitaglo MP 500 Tablet SR
This tablet contains sitagliptin, metformin, and pioglitazone, which act in different ways to bring down high blood sugar. Keeping sugar under control helps prevent serious complications of diabetes and supports better energy and health. When taken consistently with lifestyle changes, it can improve quality of life and reduce the chances of cardiovascular problems.

Possible Side Effects
Most side effects are mild and temporary. Inform your doctor if they continue or become bothersome.

Headache
Diarrhea
Upper respiratory infection
Weight gain
Swelling of feet or ankles
Low blood sugar, especially if used with insulin or sulfonylureas

How to Use
Take Sitaglo MP 500 Tablet SR in the exact dose prescribed by your doctor. Swallow the tablet whole with meals. Do not chew, crush, or break it.

How It Works

Sitagliptin increases insulin release from the pancreas, improves insulin action, and lowers excess sugar production in the liver.
Metformin decreases glucose formation in the liver, slows sugar absorption in the intestine, and improves the body’s response to insulin.
Pioglitazone increases insulin sensitivity and helps glucose move into cells for energy.
Together, they give stronger and more stable blood sugar control.

Safety Advice

Alcohol: Avoid alcohol as it may increase the risk of lactic acidosis and hypoglycemia.
Pregnancy: Use only if clearly prescribed by your doctor.
Breastfeeding: Not recommended as the drug may pass into breast milk.
Driving: Low or high blood sugar may cause dizziness or blurred vision. Avoid driving if you feel unwell.
Kidney: Should be used cautiously in patients with kidney disease. Not suitable for severe kidney impairment.
Liver: Not safe in patients with severe liver problems. Always consult your doctor.
Heart: Pioglitazone can cause fluid retention, so caution is required in patients with heart failure.

Missed Dose
If you forget to take a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed one. Do not take two doses together.