HCQS 400 Tablet

HCQS 400 Tablet – Detailed Information
Introduction

HCQS 400 Tablet contains Hydroxychloroquine, a medicine that belongs to the group of Disease-Modifying Anti-Rheumatic Drugs (DMARDs). It is widely prescribed to treat autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus (SLE). By controlling excessive immune activity, HCQS 400 helps relieve symptoms like pain, swelling, stiffness, and fatigue while slowing down the progression of these chronic conditions.

Recent studies also suggest that hydroxychloroquine may improve insulin sensitivity and beta-cell function, thereby supporting glycemic control in patients with type 2 diabetes mellitus.

Therapeutic Uses

HCQS 400 Tablet is mainly prescribed for:

Rheumatoid Arthritis – a chronic autoimmune disease that causes joint pain, swelling, and deformities.

Systemic Lupus Erythematosus (SLE) – an autoimmune disease affecting skin, joints, kidneys, heart, and other organs.

Type 2 Diabetes Mellitus (off-label use) – helps improve blood sugar control in some patients.

Benefits of HCQS 400 Tablet
In Rheumatoid Arthritis

Reduces pain, stiffness, and swelling in the joints

Improves mobility and flexibility

Prevents or delays joint damage and deformities

Enhances daily activity levels and quality of life

In Systemic Lupus Erythematosus (SLE)

Controls skin rashes and photosensitivity

Reduces fatigue and joint pain

Helps manage organ involvement (e.g., kidney, lung, or heart)

Prevents flare-ups of the disease

In Type 2 Diabetes Mellitus

Improves insulin sensitivity

Enhances pancreatic beta-cell function

Contributes to better blood sugar regulation when combined with other anti-diabetic medicines

How HCQS 400 Tablet Works

HCQS 400 is a DMARD.

It works by modulating the activity of the immune system, thereby reducing inflammation and tissue damage caused by autoimmune diseases.

It also affects lysosomal activity and antigen presentation, reducing abnormal immune responses.

Additionally, hydroxychloroquine is believed to enhance insulin action, thereby improving glycemic control in diabetes.

Dosage & Administration

Take only as prescribed by your doctor.

Swallow whole with a glass of water; do not chew, crush, or break.

Must be taken with food to reduce stomach irritation.

Take the medicine at the same time daily for maximum benefit.

Complete the full course of treatment, even if you feel better early.

Side Effects of HCQS 400 Tablet
Common Side Effects

Nausea

Vomiting

Diarrhea

Abdominal pain or cramps

Loss of appetite

Headache

Mood changes (affect lability)

Skin rash, itching, or pigmentation changes

Blurred vision or eye discomfort

Serious Side Effects (rare, but need immediate medical attention)

Severe vision changes (retinopathy, vision loss, halos around lights)

Muscle weakness

Irregular heartbeat or chest pain

Severe allergic reaction (swelling of face/lips, breathing difficulty)

Seizures

⚠️ Report any eye problems immediately. Regular ophthalmologic (eye) check-ups are essential.

Precautions and Warnings

Eye Safety

HCQS 400 may cause retinal damage with long-term use.

Contraindicated in patients with pre-existing retinal or visual field changes.

Regular eye examinations (every 6–12 months) are recommended.

Kidney and Liver Conditions

Use with caution in patients with kidney or liver disease.

Dose adjustments may be necessary.

Heart Health

Inform your doctor if you have a history of heart problems (e.g., arrhythmias).

Can rarely cause cardiomyopathy or conduction disorders.

Children

Not recommended for long-term use in children due to risk of retinal damage.

Pregnancy and Breastfeeding

Safe if prescribed – most studies show low or no risk to the baby.

Hydroxychloroquine passes into breast milk in very small amounts, but it is not harmful to infants.

Driving and Operating Machinery

Avoid driving if you experience blurred vision or dizziness.

Drug Interactions

Inform your doctor if you are taking:

Other medicines for autoimmune conditions (e.g., methotrexate)

Antidiabetic medicines – risk of low blood sugar

Antiseizure drugs

Heart medicines (e.g., digoxin, amiodarone)

Antibiotics (e.g., azithromycin, moxifloxacin) – increased risk of heart rhythm issues

Safety Advice

Alcohol: Avoid or limit alcohol; may worsen liver side effects.

Kidney Disease: Use with caution, may need dose adjustment.

Liver Disease: Use with caution, may need dose adjustment.

Pregnancy & Breastfeeding: Safe if prescribed.

Driving: Unsafe if blurred vision occurs.

Key Takeaways

HCQS 400 Tablet is an effective treatment for rheumatoid arthritis and SLE.

It improves joint health, reduces flare-ups, and slows disease progression.

Take with food, at the same time daily.

Regular eye check-ups are mandatory.

Use cautiously in patients with liver, kidney, or heart problems.

Always follow your doctor’s dosage instructions and never self-medicate.