Piosafe MF 15/500 Tablet is a prescription medicine used to manage type 2 diabetes mellitus in adults. It is a combination therapy that helps control blood sugar levels by improving the body’s response to insulin and facilitating proper utilization of glucose. Used alongside a healthy diet and regular exercise, Piosafe MF supports effective blood sugar management, helping to prevent serious complications of diabetes such as kidney damage, nerve problems, and vision issues.
Key Ingredients
Pioglitazone – improves insulin sensitivity and lowers blood glucose levels
Metformin – reduces glucose production in the liver and improves glucose absorption by the body
Uses of Piosafe MF Tablet
Treatment of type 2 diabetes mellitus
Benefits of Piosafe MF Tablet
• Helps maintain healthy blood glucose levels
• Improves the body’s response to insulin
• Reduces blood sugar spikes after meals
• Supports long-term diabetes management
• Reduces risk of diabetes-related complications like kidney damage, eye damage, and nerve problems
• Can be combined with other antidiabetic medications if needed
• Supports overall metabolic health
• Enhances energy levels and daily functioning
• Helps achieve better glycemic control when diet and exercise alone are insufficient
• Contributes to prevention of long-term complications
Side Effects of Piosafe MF Tablet
Most side effects are mild and often resolve as the body adjusts. Consult a doctor if they persist or worsen.
• Hypoglycemia (low blood sugar)
• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Edema (swelling)
• Urinary tract infection
• Upper respiratory tract infection
• Sinus infection
• Loss of appetite
How to Use Piosafe MF Tablet
• Take as prescribed by your doctor, usually once or twice daily
• Must be taken with food to avoid stomach upset
• Swallow the tablet whole; do not chew, crush, or break
• If a dose is missed, take it as soon as possible. If it is almost time for the next dose, skip the missed dose. Do not double the dose
How It Works
Piosafe MF 15/500 Tablet combines two antidiabetic agents. Pioglitazone increases insulin sensitivity in the body, while Metformin lowers glucose production in the liver and improves glucose uptake by tissues. Together, they provide comprehensive control of blood sugar levels.
Safety Advice and Precautions
• Avoid alcohol as it may increase risk of side effects
• Consult your doctor if pregnant or breastfeeding
• Use with caution in patients with kidney or liver disease; dose adjustments may be needed
• Avoid use in severe kidney or liver disease
• Monitor blood sugar regularly to prevent hypoglycemia
• Inform your doctor of all medications to prevent interactions
• Report any unusual swelling, shortness of breath, or abdominal pain
Driving and Operating Machinery
• Caution is advised if blood sugar is too low or too high, as it may affect alertness
Missed Dose
• Take as soon as possible unless it is nearly time for your next dose.
• Do not double the dose to make up for a missed one





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