Bactrim DS Tablet
Product Overview
Bactrim DS Tablet is a broad-spectrum antibiotic used to treat a wide variety of bacterial infections affecting the urinary tract, respiratory tract, skin, ears, lungs, brain, and gastrointestinal system. It is also effective against toxoplasmosis and Pneumocystis pneumonia (PCP), particularly in individuals with weakened immunity.
Unlike antiviral medicines, Bactrim DS Tablet does not work against viral infections such as colds or the flu.
This medicine combines Trimethoprim and Sulfamethoxazole, two powerful antibiotics that work synergistically to stop bacterial growth and eliminate infection. Together, they help relieve symptoms, control infection spread, and support faster recovery.
Mechanism of Action
Bactrim DS Tablet contains:
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Trimethoprim – Blocks the formation of tetrahydrofolic acid, a vital nutrient bacteria need for DNA synthesis.
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Sulfamethoxazole – Prevents the production of dihydrofolic acid, another key compound required for bacterial survival.
By inhibiting these pathways, the medicine halts bacterial growth and replication, effectively killing the infection-causing organisms.
Therapeutic Uses
Bactrim DS Tablet is prescribed for the treatment and management of:
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Urinary Tract Infections (UTIs) caused by susceptible bacterial strains
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Respiratory tract infections such as bronchitis and pneumonia
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Ear infections (otitis media) and related inflammation
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Skin and soft tissue infections, including infected cuts or surgical wounds
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Gastrointestinal infections due to Shigella or Salmonella species
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Toxoplasmosis and Pneumocystis pneumonia (PCP) in immunocompromised patients
Key Benefits
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Broad-spectrum protection against gram-positive and gram-negative bacteria
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Helps relieve infection-related symptoms such as pain, swelling, and fever
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Prevents bacterial multiplication and recurrence
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Useful for patients with both common and complex bacterial infections
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Clinically proven combination for fast, targeted action
Directions for Use
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Take Bactrim DS Tablet with or without food, as directed by your doctor.
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Swallow the tablet whole with a glass of water.
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Do not crush, chew, or break it.
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Follow the prescribed dosage schedule strictly for best results.
If you forget a dose, take it as soon as possible. Skip it if your next dose is due—do not double up.
Possible Side Effects
Most side effects are mild and temporary. Commonly reported ones include:
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Nausea or vomiting
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Headache or dizziness
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Loss of appetite
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Mild skin rash or hives
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Diarrhoea or stomach discomfort
If any side effect persists or worsens, contact your healthcare provider immediately.
Precautions & Safety Advice
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Allergies: Avoid if you are allergic to sulfonamides, trimethoprim, or any ingredient in the tablet.
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Kidney/Liver Disorders: Use only under medical supervision if you have kidney or liver disease.
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Pregnancy & Breastfeeding: Not recommended unless prescribed by a doctor.
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Children: Not suitable for those under 12 years of age.
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Alcohol: Avoid alcohol to prevent adverse reactions such as nausea, flushing, or rapid heartbeat.
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Medical Conditions: Inform your doctor if you have asthma, thyroid disorders, diabetes, or folic acid deficiency.
Diet & Lifestyle Advice
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Take probiotic-rich foods such as yogurt, kefir, and fermented vegetables to restore healthy gut flora.
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Eat fibre-rich foods (whole grains, fruits, lentils) to improve digestion.
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Avoid grapefruit, dairy, and high-calcium foods close to dosing time—they may interfere with absorption.
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Refrain from smoking and alcohol during treatment.
Storage Instructions
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Store in a cool, dry place between 10°C and 25°C, away from direct sunlight.
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Keep out of reach of children and pets.
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Do not use if the packaging is damaged or expired.
Overdose Information
Do not exceed the prescribed dose. Symptoms of overdose may include dizziness, nausea, vomiting, confusion, drowsiness, or loss of appetite.
Seek immediate medical attention if overdose is suspected.
Drug Interactions
Bactrim DS Tablet may interact with:
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ACE inhibitors (e.g., Enalapril) – may increase potassium levels
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Anticoagulants (Warfarin) – may enhance bleeding risk
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Oral antidiabetic agents – may cause hypoglycaemia
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BCG vaccine or other live vaccines – effectiveness may be reduced
Always inform your doctor about any ongoing medications or supplements.
Product Summary
| Attribute | Description |
|---|---|
| Therapeutic Class | Antibiotic Combination |
| Active Ingredients | Trimethoprim + Sulfamethoxazole |
| Indication | Bacterial Infections (UTI, RTI, Skin, GI, PCP) |
| Form | Tablet |
| Habit Forming | No |
| Storage Temperature | 10°C – 25°C |






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