Amphotret 50 mg Injection 1*1

**About Amphotret 50 mg Injection**

Amphotret 50 mg Injection is a **prescription antifungal medicine** used to treat **serious systemic fungal infections**. It is commonly prescribed for infections caused by **Candida, Aspergillus, and other susceptible fungi**, especially in patients with weakened immune systems, such as those undergoing chemotherapy, organ transplantation, or severe infections in hospitalized patients.

The injection contains **Amphotericin B**, a broad-spectrum antifungal agent that works by **binding to fungal cell membranes and disrupting their integrity**, leading to the death of the fungal cells.

**Medicinal Benefits**

* **Treats Systemic Fungal Infections:** Effective against severe fungal infections that affect blood, lungs, kidneys, and other organs.
* **Rapid Action:** Quickly controls fungal growth and prevents further spread of infection.
* **Protects Immunocompromised Patients:** Critical for patients with weakened immunity due to illness or medical treatment.
* **Prevents Complications:** Helps reduce the risk of organ failure and sepsis caused by systemic fungal infections.

**How Amphotret 50 mg Injection Works**
Amphotericin B binds to **ergosterol**, a key component of fungal cell membranes. This binding creates pores in the membrane, causing leakage of essential cellular components and ultimately killing the fungal cells. Its action is selective for fungi, minimizing damage to human cells.

**Directions for Use**

* Administered **intravenously (IV)** by a healthcare professional only.
* Dosage and duration depend on the type and severity of infection, patient weight, and response to therapy.
* Should be diluted and infused slowly as per medical guidelines.

**Possible Side Effects**

* Fever, chills, or shivering during infusion
* Nausea and vomiting
* Headache
* Low blood pressure or rapid heart rate
* Kidney toxicity (monitor kidney function regularly)
* Electrolyte imbalance, including low potassium or magnesium

**Safety Advice & Precautions**

* Only for **intravenous use under medical supervision**.
* Inform your doctor if you have **kidney or liver problems**, heart conditions, or electrolyte imbalance.
* Regular monitoring of **kidney function, liver function, and electrolytes** is required during therapy.
* Pregnant or breastfeeding women should use only if clearly indicated and under strict medical supervision.
* Avoid concurrent use of nephrotoxic drugs unless monitored closely.

**Storage Instructions**
Store **below 25°C**, protected from light and moisture. Do not freeze. Keep out of reach of children.

**Uses**

* Systemic Candida infections
* Aspergillosis
* Cryptococcal infections
* Life-threatening fungal infections in immunocompromised patients

**Product Variants & Keywords**
Amphotret 50 mg Injection, Amphotericin B 50 mg IV, Amphotret Antifungal Injection, Amphotret for Systemic Fungal Infections, Amphotericin B Infusion, Amphotret 50 mg IV Therapy.