Cefrine Plus 1000 mg/500 mg Injection

Cefrine Plus 1000 mg/500 mg Injection is a prescription medicine used for the treatment of moderate to severe bacterial infections in different parts of the body such as the lungs, urinary tract, skin, bones, joints, blood, abdomen, and reproductive organs. It contains ceftriaxone, a third-generation cephalosporin antibiotic, and sulbactam, a beta-lactamase inhibitor. This powerful combination ensures broader coverage by not only killing harmful bacteria but also preventing them from resisting antibiotic action. It is usually administered in a hospital or clinical setting under the supervision of a healthcare professional. Cefrine Plus Injection is effective against both gram-positive and gram-negative bacteria, offering quick relief from fever, pain, inflammation, and infection-related discomfort. It is commonly used in conditions such as pneumonia, septicemia, urinary tract infections, skin infections, surgical site infections, and gynecological infections. Timely administration and completing the prescribed course are essential to achieve complete bacterial clearance and avoid resistance.

Benefits

• Provides dual action with antibiotic and resistance inhibitor

• Effective in treating respiratory infections including pneumonia and bronchitis

• Controls urinary tract and bladder infections

• Useful in bacterial skin and soft tissue infections

• Helps manage bone and joint infections

• Effective in intra-abdominal infections

• Works in septicemia and other bloodstream infections

• Reduces fever and discomfort caused by bacterial illness

• Prevents bacterial growth and resistance simultaneously

• Useful in gynecological and reproductive tract infections

• Helps in post-surgical infection control

• Provides faster recovery compared to single antibiotic use

• Suitable for hospital-acquired and community-acquired infections

• Reduces chances of relapse of bacterial illness

• Ensures broad-spectrum bacterial coverage

Possible Side Effects

• Pain, redness, or swelling at the injection site

• Mild diarrhea or loose stools

• Stomach discomfort or nausea

• Headache or dizziness

• Mild rash or itching

• Fever or chills in rare cases

• Allergic reaction with swelling or breathing difficulty in uncommon cases

• Altered liver enzyme or kidney function in prolonged use

How To Use

• Given only by a doctor or nurse through injection into a vein or muscle

• Dosage and frequency depend on the severity of infection and patient condition

• Must be administered at regular intervals for best results

• Do not self-administer the injection at home unless advised

• Complete the full prescribed course even if symptoms improve early

• Store vials as instructed by manufacturer in a cool and dry place

How It Works

• Ceftriaxone weakens bacterial cell wall formation, leading to destruction of bacteria

• Sulbactam blocks enzymes (beta-lactamases) produced by bacteria to resist antibiotics

• Together they ensure enhanced and prolonged antibacterial activity

• This dual mechanism clears infection faster and prevents recurrence

What To Avoid

• Avoid stopping the treatment course midway without doctor’s advice

• Avoid alcohol during the treatment as it may worsen side effects

• Avoid self-injecting without medical supervision

• Avoid skipping doses in scheduled treatment

• Avoid combining with other antibiotics unless prescribed

• Avoid use if there is history of allergy to cephalosporins or penicillins

• Avoid use in viral or fungal infections as it will not be effective

• Avoid using expired or improperly stored vials

• Avoid overdosage as it may cause serious side effects

• Avoid ignoring severe diarrhea or allergic reactions

Safety Advice

• Strictly use under medical supervision in hospital or clinic

• Inform doctor about any existing liver or kidney problems

• Pregnant or breastfeeding women should use only under doctor’s guidance

• Patients on blood thinners or heart medicines should inform their doctor

• Regular monitoring may be required in long-term treatment

• Maintain hydration during therapy for better kidney protection

• Report any unusual symptoms such as rashes, swelling, or difficulty breathing immediately

• Not recommended for self-use at home unless specifically advised

• Keep medicine away from children’s reach

• Complete follow-up checkups for better recovery outcomes

Precautions

• Not suitable for patients with known allergy to cephalosporins or related antibiotics

• Use carefully in patients with a history of severe gastrointestinal issues

• Patients with seizure disorders should be monitored closely

• Dosage adjustment may be required in kidney or liver impairment

• Prolonged use may lead to overgrowth of resistant organisms

• Seek immediate help in case of severe rash, jaundice, or breathing trouble

• Avoid unnecessary use to prevent antibiotic resistance

• Always follow sterile technique during injection to avoid secondary infections

• Do not use leftover vials from previous treatment

• Use only as prescribed and under proper medical observation