DUOPIL 1/500

Introduction

Duopil 1/500 Tablet PR is an anti-diabetic medicine prescribed for adults with type 2 diabetes mellitus. It contains two active components that work together to regulate blood sugar levels. Keeping glucose under control with this medicine helps reduce the chances of long-term diabetes complications.

This tablet should always be taken with meals and at the same time each day for maximum effect. The dose is decided by your doctor based on your response and blood sugar readings. Even if you feel fine or your sugar levels look stable, continue taking the medicine unless your doctor advises otherwise. Stopping treatment without medical guidance may cause your blood sugar to rise again and increase the risk of kidney, eye, nerve, or limb damage. Along with medication, lifestyle changes such as a balanced diet, regular exercise, and maintaining a healthy weight are important for good diabetes control.

Benefits

The combination in Duopil 1/500 Tablet PR helps lower blood glucose in different ways. One component increases insulin release from the pancreas, while the other reduces glucose production in the liver and enhances insulin sensitivity. Together, they help your body use sugar more effectively. Consistent use of this medicine lowers the risk of serious problems like kidney disease, nerve weakness, or vision loss, and supports a healthier life when combined with proper diet and activity.

Possible side effects

Some people may experience low blood sugar (hypoglycemia). Signs include sweating, dizziness, trembling, or headache. To prevent this, do not skip meals and always carry a quick source of sugar such as fruit juice or candy. Drinking alcohol raises the chance of low sugar levels and should be avoided. Other effects that might appear include nausea, diarrhea, stomach upset, changes in taste, headache, minor weight gain, or respiratory infections. Most of these are temporary and improve with time.

How to take

Swallow the tablet whole with water while eating food. Follow the schedule given by your doctor, and do not crush or chew the tablet.

How it works

This medicine contains two well-known antidiabetic agents: Glimepiride, which stimulates the pancreas to release more insulin, and Metformin, which reduces glucose formation in the liver, delays sugar absorption from the gut, and improves insulin response in the body.

Precautions

This medicine is not suitable for people with type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver problems. Inform your doctor if you have heart disease or a history of organ issues. Pregnant and breastfeeding women should only use it under medical supervision. Blood sugar should be monitored regularly, and periodic blood tests may be required to check kidney and liver function.

Missed dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue as usual. Do not take two tablets at the same time to make up for a missed dose.

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