Istamet Xr 500 1*10Tab

Istamet XR 500 Tablet is a combination medicine used to manage type 2 diabetes mellitus in adults. It helps control blood sugar levels when diet and exercise alone are not effective. The tablet contains Sitagliptin and Metformin (extended-release), which work together to improve insulin function and reduce glucose production in the body.

Istamet XR 500 Tablet should be taken with food, preferably in the evening, to minimize stomach upset. Swallow the tablet whole with water—do not crush or chew it. The dose and duration are determined by your doctor based on your blood sugar levels and response to treatment. Do not stop taking the medicine without consulting your doctor, as this may worsen your diabetes.

Uses of Istamet XR 500 Tablet

Treatment of type 2 diabetes mellitus

Helps control and maintain healthy blood sugar levels

Benefits of Istamet XR 500 Tablet
Istamet XR 500 Tablet helps improve the body’s natural response to insulin after meals and lowers sugar produced by the liver. It provides stable blood glucose control throughout the day and reduces the risk of diabetes complications such as nerve damage, kidney problems, and heart disease. Regular use, along with a balanced diet and physical activity, enhances the effectiveness of this medicine.

Side Effects of Istamet XR 500 Tablet
Most side effects are mild and temporary. If they persist or cause concern, contact your doctor.

Common side effects include:

Nausea or vomiting

Stomach discomfort

Diarrhea

Headache

Dizziness

Low blood sugar (especially if taken with other anti-diabetic medicines)

How to Use Istamet XR 500 Tablet
Take the tablet with food to reduce stomach irritation.
Swallow it whole with water; do not crush, chew, or break it.
Take it at the same time each day to maintain consistent blood sugar control.
Follow your doctor’s instructions carefully and do not skip doses.

How Istamet XR 500 Tablet Works
Istamet XR 500 Tablet combines two anti-diabetic medicines — Sitagliptin and Metformin.

Sitagliptin is a DPP-4 inhibitor that increases the release of insulin and decreases the release of glucagon (a hormone that raises blood sugar).

Metformin (extended-release) reduces glucose production in the liver and improves the body’s response to insulin.
Together, they help regulate blood sugar levels effectively throughout the day.

Safety Advice

Alcohol:
Avoid excessive alcohol while taking this medicine, as it may increase the risk of low blood sugar and lactic acidosis.

Pregnancy:
Consult your doctor before use. Your doctor will decide whether this medicine is safe during pregnancy based on your condition.

Breastfeeding:
Use only if prescribed by your doctor. Limited data suggest that small amounts of the medicine may pass into breast milk.

Driving:
Be cautious while driving or operating machines, as low blood sugar can cause dizziness, blurred vision, or confusion.

Kidney and Liver:
Use with caution in patients with kidney or liver disease. Regular monitoring of kidney function is advised. Dose adjustments may be necessary.

Missed Dose:
If you miss a dose, take it as soon as you remember. If it is almost time for the next one, skip the missed dose and continue your regular schedule. Do not double up to make up for a missed dose.