Macsita-M 50/500 Tablet
Macsita-M 50/500 Tablet is a combination medicine designed to manage type 2 diabetes effectively. It contains Metformin and Sitagliptin, which work together to help control blood sugar levels. Metformin reduces glucose production in the liver and improves the body’s sensitivity to insulin, allowing cells to absorb and use sugar more efficiently. Sitagliptin enhances insulin release in response to meals and reduces excessive sugar production in the liver. This dual-action combination is particularly useful for patients who require better blood sugar control when lifestyle modifications alone are not enough. Regular intake under medical supervision, along with a healthy diet, exercise, and routine blood sugar monitoring, ensures optimal diabetes management, reduces the risk of complications like neuropathy, kidney issues, and cardiovascular disease, and supports long-term metabolic health and overall well-being.
Benefits
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Helps in controlling blood sugar levels in type 2 diabetes 
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Reduces excessive glucose production in the liver 
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Improves insulin sensitivity in body cells 
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Enhances insulin release after meals 
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Supports better glucose utilization by the body 
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Reduces risk of diabetes-related complications 
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Helps in managing HbA1c levels over long term 
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Provides dual-action mechanism for effective control 
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Can be used alongside diet and exercise programs 
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Promotes energy levels by improving sugar metabolism 
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Reduces excessive thirst and frequent urination 
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Helps maintain steady blood sugar throughout the day 
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Improves overall metabolic balance 
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Supports cardiovascular and kidney health in diabetic patients 
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Suitable for adults under medical guidance 
Possible Side Effects
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May cause mild nausea or vomiting 
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Can lead to abdominal discomfort or bloating 
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Sometimes causes diarrhea 
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May result in loss of appetite 
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Possible headache or dizziness in initial days 
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Rare allergic reactions such as rash or itching 
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Can cause mild fatigue or weakness 
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Rare cases of hypoglycemia if combined with other diabetic medicines 
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Possible metallic taste in mouth 
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Rare vitamin B12 deficiency with long-term use 
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Possible lactic acidosis in very rare cases 
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May lead to bloating or gas 
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Rare swelling or discomfort in stomach area 
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Possible mild changes in liver enzymes 
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Uncommon low blood sugar symptoms like sweating or shakiness 
How to Use
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Take exactly as prescribed by the doctor 
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Swallow tablet with water, preferably after meals 
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Maintain the same timing every day for consistent control 
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Do not skip or double doses 
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Continue even if blood sugar appears normal 
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Monitor blood sugar regularly 
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Store in a cool, dry place away from sunlight 
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Keep out of reach of children 
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If a dose is missed, take it as soon as remembered unless near next dose 
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Do not crush or chew unless advised 
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Maintain a healthy diet and regular exercise program 
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Avoid self-adjusting dose 
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Follow routine blood sugar check-ups 
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Do not combine with other medicines without consulting doctor 
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Complete full course for effective management 
How it Works
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Metformin decreases glucose production in the liver 
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Improves insulin sensitivity in muscle and fat cells 
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Sitagliptin enhances insulin release after meals 
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Reduces excessive sugar production in the liver 
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Helps maintain stable blood glucose levels throughout the day 
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Reduces post-meal blood sugar spikes 
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Supports long-term HbA1c control 
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Prevents complications related to high blood sugar 
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Provides combined effect for optimal diabetes management 
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Improves overall metabolic function 
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Reduces symptoms like excessive thirst, urination, and fatigue 
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Supports kidney and cardiovascular health 
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Maintains energy balance by proper glucose utilization 
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Enhances quality of life for type 2 diabetic patients 
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Ensures safer blood sugar control than single-drug therapy 
What to Avoid
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Avoid alcohol as it may increase risk of lactic acidosis 
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Avoid skipping meals while taking the medicine 
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Avoid high-sugar or processed foods 
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Avoid self-adjusting dose without doctor consultation 
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Avoid combining with other diabetes medicines unless prescribed 
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Avoid dehydration or skipping fluids 
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Avoid excessive caffeine intake 
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Avoid herbal or over-the-counter supplements without doctor advice 
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Avoid ignoring signs of low blood sugar 
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Avoid high-fat meals that reduce medicine absorption 
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Avoid self-medication for diabetes 
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Avoid sudden changes in diet without guidance 
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Avoid using expired tablets 
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Avoid combining with contrast dye for imaging unless approved 
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Avoid ignoring persistent gastrointestinal discomfort 
Safety Advice
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Take only under strict medical supervision 
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Pregnant or breastfeeding women should consult doctor before use 
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Elderly patients should monitor kidney function regularly 
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Patients with kidney or liver disease need close supervision 
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Regular blood sugar and HbA1c monitoring is advised 
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Maintain adequate hydration 
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Report unusual symptoms such as weakness or dizziness 
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Do not self-adjust dose 
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Keep medicine stored safely in original packaging 
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Follow diet, exercise, and lifestyle recommendations 
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Avoid combining with other medicines unless advised 
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Routine medical follow-ups are essential 
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Be cautious about signs of hypoglycemia 
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Carry glucose or sugar source in case of low blood sugar 
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Ensure awareness of lactic acidosis symptoms, though rare 
Precautions
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Take only in prescribed dose and duration 
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Inform doctor about allergies or other medical conditions 
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Report persistent nausea, vomiting, or diarrhea 
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Avoid sudden lifestyle changes that affect blood sugar 
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Monitor kidney and liver function if on long-term use 
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Avoid combining with other medications without doctor consultation 
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Ensure regular blood sugar and HbA1c tests 
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Do not stop medication abruptly 
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Maintain healthy diet and physical activity 
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Be aware of low blood sugar symptoms and treat promptly 
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Avoid alcohol and excessive caffeine 
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Follow proper storage instructions 
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Complete full course for best results 
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Use cautiously in elderly or kidney-impaired patients 
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Regular medical review is essential for safe long-term use 

 
										 
										 
            
 
		                  


 
				 
				 
				 
				 
				 
				 
				
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