Pramipex ER 0.375 Tablet is a prescription medicine used in the treatment of Parkinson’s disease and Restless Leg Syndrome (RLS). It helps relieve symptoms like tremors, stiffness, and difficulty in movement by improving muscle control and coordination. The extended-release (ER) formulation provides a steady release of the medicine throughout the day, maintaining consistent therapeutic levels and ensuring prolonged relief.
It works by mimicking the effects of dopamine, a natural brain chemical essential for controlling body movement, balance, and coordination. By restoring dopamine activity, Pramipex ER 0.375 Tablet improves daily functioning, reduces involuntary movements, and promotes better sleep quality in people with RLS.
Key Ingredient:
Pramipexole Dihydrochloride (Extended Release)
Key Benefits:
• Helps control tremors, stiffness, and slowness of movement in Parkinson’s disease
• Improves coordination, balance, and mobility
• Reduces leg discomfort and restlessness in Restless Leg Syndrome
• Provides long-lasting symptom relief due to extended-release formulation
• Enhances daily functioning and quality of life
• Promotes better sleep by reducing leg movements at night
• Supports smoother and more controlled body movements
• May delay the need for higher doses of levodopa in early Parkinson’s treatment
• Reduces fatigue and muscle rigidity
• Improves concentration and overall comfort during waking hours
How to Use:
• Take the medicine exactly as prescribed by your doctor
• Swallow the tablet whole with water — do not crush, chew, or break it
• It is best taken with food to prevent nausea
• Try to take it at the same time every day for consistent results
• Do not stop this medication suddenly without consulting your doctor
How It Works:
Pramipex ER 0.375 Tablet is a dopamine agonist. It acts by stimulating dopamine receptors in the brain, mimicking the effect of dopamine. This action helps reduce motor symptoms in Parkinson’s disease and relieves the unpleasant sensations and movement urges seen in Restless Leg Syndrome.
Possible Side Effects:
• Dizziness or light-headedness
• Sleepiness or sudden sleep attacks
• Nausea or vomiting
• Dry mouth
• Fatigue or weakness
• Hallucinations (seeing or hearing things that aren’t real)
• Constipation
• Insomnia (trouble sleeping)
• Headache
• Peripheral edema (swelling of legs or feet)
Most of these effects are temporary and resolve as the body adapts to the medicine. Contact your doctor if side effects persist or become severe.
What to Avoid:
• Avoid alcohol as it increases drowsiness and dizziness
• Avoid driving or operating heavy machinery until you know how the medicine affects you
• Avoid abrupt discontinuation — stopping suddenly may worsen symptoms
• Avoid combining with sedatives or other dopamine agonists without medical advice
• Avoid excessive caffeine or nicotine, which can aggravate restlessness
Safety Advice:
• Alcohol: Unsafe — may cause excessive drowsiness or dizziness
• Pregnancy: Consult your doctor — may be unsafe during pregnancy
• Breastfeeding: Not recommended — may suppress milk production
• Driving: Unsafe — may cause hallucinations, sleep attacks, or loss of focus
• Kidney: Use with caution; dose adjustment may be required in kidney disease
• Liver: Generally safe if prescribed; consult your doctor if you have liver problems
Precautions:
• Use under strict medical supervision only
• Inform your doctor about any history of mental illness, hallucinations, or impulse control issues
• Report any unusual urges such as gambling, increased sexual desire, or compulsive spending immediately
• Keep out of reach of children
• Store in a cool, dry place away from direct sunlight
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