Ryzodeg 100IU/ml Penfill

Ryzodeg 100IU/ml Penfill is an insulin combination used to manage type 1 and type 2 diabetes mellitus in adults and children. It contains two types of insulin — one that acts quickly after injection and another that provides a long-lasting effect. Together, they help maintain balanced blood sugar levels throughout the day and night.

Composition
Each ml of Ryzodeg Penfill contains:

• Insulin degludec (long-acting insulin)

• Insulin aspart (rapid-acting insulin)

These components work together to control blood sugar spikes after meals while providing a continuous insulin supply for up to 24 hours.

Uses

• Helps regulate blood sugar levels in diabetes

• Reduces the risk of sudden high or low glucose levels

• Provides flexibility in insulin management for both type 1 and type 2 diabetic patients

How It Works
Insulin degludec maintains a steady background insulin level throughout the day, while insulin aspart quickly lowers blood sugar after food intake. This dual action helps muscles and fat cells absorb sugar effectively and reduces sugar production by the liver.

Dosage and Administration
Ryzodeg is administered subcutaneously (under the skin) as directed by your doctor. It is usually taken once daily, at the same time each day. If necessary, it can be injected at another time, keeping at least an 8-hour gap between doses. Your doctor or nurse will show you the correct injection technique using the Penfill cartridge with an insulin delivery pen. Never inject directly into a vein or muscle unless specifically advised.

Benefits

• Combines long-term and fast insulin action in one injection

• Helps maintain stable glucose levels day and night

• Lowers risk of nocturnal hypoglycemia (low blood sugar during sleep)

• Reduces the number of daily injections compared to separate insulins

• Improves convenience and flexibility in diabetes control

Possible Side Effects
Most side effects are mild and go away with regular use. Common ones include:

• Low blood sugar (hypoglycemia)

• Pain, redness, or swelling at the injection site

• Skin thickening or dimples (lipodystrophy)

• Mild rash or itching

• Fluid retention or slight weight gain

If symptoms persist or become severe, inform your healthcare provider.

Safety Advice
Avoid alcohol as it can cause a sudden drop in blood sugar.
Pregnant or breastfeeding women should use it only under medical supervision.
It is generally safe for patients with kidney or liver problems but requires regular monitoring of sugar levels.
Avoid driving or operating machinery if you feel dizzy or confused due to low or high blood sugar.

Missed Dose
If you forget a dose, take it with your next major meal. Do not take an extra dose to make up for the missed one.

Lifestyle Support
For effective diabetes control, combine Ryzodeg use with a balanced diet rich in fiber and low in refined sugars, regular physical activity, routine blood sugar checks, and adequate hydration and rest.