Sitanorm-D 100/10 Tablet

Sitanorm-D 100/10 Tablet – Detailed Overview
Product Introduction

Sitanorm-D 100/10 Tablet is an oral combination medicine used for the management of Type 2 diabetes mellitus. This condition arises when the body either cannot produce enough insulin or cannot use insulin effectively, resulting in elevated blood sugar levels.

Uncontrolled diabetes can lead to serious complications, including:

Kidney damage (nephropathy)

Eye damage (retinopathy and potential blindness)

Nerve damage (neuropathy)

Cardiovascular complications (heart attack, stroke)

Sitanorm-D 100/10 Tablet is prescribed alongside diet, exercise, and lifestyle modifications to achieve optimal blood glucose control in adults. It may be used when other treatments alone are insufficient.

Composition

Active Ingredients:

Dapagliflozin 10 mg – SGLT2 inhibitor

Sitagliptin 100 mg – DPP-4 inhibitor

Form: Tablet

Category: Oral antidiabetic combination

Mechanism of Action

Sitanorm-D 100/10 Tablet works via two complementary mechanisms to control blood sugar:

Dapagliflozin: Increases the excretion of glucose through urine, lowering blood sugar levels independent of insulin.

Sitagliptin: Enhances insulin release from the pancreas when blood sugar is elevated and suppresses glucagon secretion from the liver, reducing hepatic glucose production.

Together, these effects improve glycemic control and reduce the risk of diabetes-related complications.

Indications / Uses

Primary Use:

Treatment of Type 2 diabetes mellitus in adults.

Secondary Benefits:

Supports proper insulin function in the body.

Helps prevent complications like kidney damage, eye damage, neuropathy, and cardiovascular events.

Can reduce blood sugar levels in patients inadequately controlled on diet, exercise, or monotherapy.

Target Patients:

Adults with Type 2 diabetes needing combination therapy.

Patients at risk of cardiovascular or kidney complications from uncontrolled blood sugar.

Dosage and Administration

Route: Oral

Dose: As prescribed by your healthcare provider.

Timing: Take at the same time every day for consistent blood sugar control.

Food: Can be taken with or without food, although a fixed routine is preferable.

Important Instructions:

Swallow the tablet whole; do not crush, chew, or split.

Do not stop taking the medication without consulting your doctor, as this may increase blood sugar and risk complications.

Continue diet, exercise, and weight management programs recommended by your healthcare provider.

Side Effects

Most side effects are mild and usually resolve as the body adjusts to the medication. Consult your doctor if they persist or worsen.

Common Side Effects:

Vaginal yeast infection

Nasopharyngitis (inflammation of throat and nasal passages)

Urinary tract infection

Upper respiratory tract infection (sore throat, cough, cold)

Headache

Precautions:

Drink plenty of fluids to prevent dehydration.

Maintain good hygiene to prevent genital fungal infections.

Warnings and Precautions

Alcohol: Safety is not established; consult your doctor.

Pregnancy: Use only if clearly needed; consult your doctor.

Breastfeeding: Safety not established; consult your doctor.

Driving: The effect on alertness and reaction time is unknown; avoid driving if affected.

Kidney Disease: Limited data; consult your doctor. Dose adjustment may be necessary.

Liver Disease: Limited data; consult your doctor.

Drug Interactions:

Inform your doctor about all medications, including supplements, to avoid interactions.

Monitoring

Blood glucose: Regular self-monitoring and laboratory testing.

Kidney function: Periodic tests advised, especially in patients with existing renal issues.

Overall diabetes management: Regular follow-ups for dose adjustment and efficacy.

Lifestyle Recommendations

Maintain a balanced diet and avoid excess sugar.

Exercise regularly to improve insulin sensitivity.

Avoid excessive alcohol consumption.

Be aware of symptoms of high or low blood sugar.

Storage

Store in a cool, dry place, away from sunlight.

Keep out of reach of children.

Maintain storage temperature below 30°C unless otherwise advised.

Summary

Sitanorm-D 100/10 Tablet is an effective combination therapy for Type 2 diabetes, working by enhancing insulin secretion and promoting glucose excretion. When combined with diet and lifestyle changes, it helps reduce blood sugar levels and prevents long-term complications, supporting overall health.

Key Points:

Take at the same time each day.

Monitor blood sugar regularly.

Be aware of side effects, especially signs of low blood sugar.

Follow lifestyle recommendations for optimal diabetes management.