Sitanorm-M 50mg/500mg Tablet SR

Sitanorm-M 50mg/500mg Tablet SR – Detailed Overview
Product Introduction

Sitanorm-M 50mg/500mg Tablet SR is a dual-action antidiabetic medication used to manage Type 2 Diabetes Mellitus (T2DM) in adults. It combines two active agents that work together to control high blood sugar levels, helping prevent serious complications of diabetes such as kidney damage, vision problems, nerve damage, and cardiovascular issues including heart attack and stroke.

This medicine is usually prescribed when diet, exercise, or other medicines alone are not sufficient to control blood sugar levels effectively.

Composition

Sitagliptin 50 mg – DPP-4 inhibitor

Metformin 500 mg – Biguanide

Form: Sustained Release (SR) Tablet
Category: Antidiabetic combination therapy

Mechanism of Action

Sitanorm-M 50mg/500mg SR works through two complementary mechanisms:

Sitagliptin:

Stimulates the pancreas to release insulin when blood glucose is high

Reduces excess sugar production by the liver

Metformin (SR):

Lowers glucose production in the liver

Delays absorption of glucose from the intestines

Increases the body’s sensitivity to insulin

The sustained-release formulation allows gradual absorption, helping maintain steady blood sugar levels throughout the day.

Indications / Uses

Primary Use: Management of Type 2 Diabetes Mellitus

Secondary Benefits:

Reduces risk of diabetes-related complications such as kidney disease, eye problems, and nerve damage

Supports cardiovascular health by helping to lower blood sugar and reduce associated risks

Promotes long-term glycemic stability

Dosage and Administration

Route: Oral

Dose: As prescribed by your doctor

Food: Take with meals to reduce gastrointestinal side effects

Timing: Take at the same time each day for consistent effect

Important Instructions:

Swallow whole; do not crush, chew, or break

Do not stop the medicine without consulting your doctor

Combine therapy with diet, exercise, and lifestyle modifications

Side Effects

Most side effects are mild and temporary. Contact your doctor if they persist.

Common Side Effects:

Diarrhea

Headache

Upper respiratory tract infection

Low blood sugar (hypoglycemia) if combined with insulin or sulfonylurea

Patient Advice:

Recognize symptoms of hypoglycemia: dizziness, sweating, palpitations, confusion

Maintain adequate hydration

Report persistent gastrointestinal discomfort

Warnings and Precautions

Alcohol: Unsafe; may increase risk of hypoglycemia or lactic acidosis

Pregnancy & Breastfeeding: Consult your doctor; limited safety data available

Driving: Blood sugar fluctuations may affect alertness; avoid driving if symptomatic

Kidney Disease: Use with caution; dose adjustment may be required; avoid in severe kidney disease

Liver Disease: Unsafe; should be avoided in patients with liver impairment

Drug Interactions: Inform your doctor about all medications, supplements, and herbal products

How It Works

Sitagliptin: Enhances insulin secretion and reduces glucagon production, lowering liver glucose output

Metformin (SR): Reduces liver glucose production, delays intestinal glucose absorption, and improves insulin sensitivity

Together, the combination ensures multi-targeted blood sugar control, particularly for patients inadequately controlled on single therapy.

Storage Instructions

Store in a cool, dry place away from direct sunlight

Keep out of reach of children

Maintain room temperature (preferably below 30°C)

Summary

Sitanorm-M 50mg/500mg Tablet SR is a dual-action, sustained-release antidiabetic medication that:

Controls high blood sugar in adults with Type 2 diabetes

Helps prevent diabetes-related complications

Provides steady, long-term glycemic control

Works best alongside a proper diet and exercise program

Patient Guidance:

Take at the same time every day

Monitor blood sugar levels regularly

Follow diet, exercise, and medical advice for optimal results

Report any persistent or severe side effects to your healthcare provider