Sitapride-M 100/500 Tablet SR

Sitapride-M 100/500 Tablet SR – Detailed Overview
Product Introduction

Sitapride-M 100/500 Tablet SR is a combination antidiabetic medicine used to manage Type 2 Diabetes Mellitus (T2DM) in adults. It helps control high blood sugar levels, preventing serious complications such as kidney damage, vision problems, nerve damage, and may reduce the risk of heart attack or stroke.

This medicine works best when combined with a healthy diet, regular exercise, and weight management, as part of a comprehensive diabetes care plan.

Composition

Sitagliptin 100 mg – DPP-4 inhibitor

Metformin 500 mg (Sustained Release) – Biguanide

Form: Tablet SR (Sustained Release)
Category: Antidiabetic combination therapy

Mechanism of Action

Sitapride-M 100/500 Tablet SR combines two complementary mechanisms to lower blood sugar:

Sitagliptin:

Stimulates the pancreas to release more insulin

Reduces glucagon production in the liver

Helps regulate post-meal and fasting blood sugar levels

Metformin (SR):

Reduces glucose production by the liver

Delays glucose absorption from the intestines

Increases insulin sensitivity in muscles and tissues

Together, these actions provide better blood sugar control than either drug alone.

Indications / Uses

Primary Use: Management of Type 2 Diabetes Mellitus in adults

Additional Benefits:

Reduces risk of diabetes-related complications (kidney, eyes, nerves)

Helps maintain cardiovascular health

Supports long-term diabetes management

Dosage and Administration

Route: Oral

Dose: As prescribed by your doctor

Timing: Take at the same time each day

Food: Take with meals to reduce stomach upset

Important Instructions:

Swallow the tablet whole, do not crush, chew, or break

Do not stop taking the medicine without consulting your doctor

Maintain a healthy lifestyle and follow your doctor’s dietary advice

Side Effects

Most side effects are mild and temporary, disappearing as your body adjusts. Contact your doctor if they persist.

Common Side Effects:

Diarrhea

Upper respiratory tract infection

Headache

Additional Advice:

Monitor for low blood sugar (hypoglycemia) if taking other antidiabetic medicines

Maintain good hydration and hygiene

Warnings and Precautions

Alcohol: Unsafe; may worsen blood sugar control

Pregnancy & Breastfeeding: Consult your doctor; limited data available

Driving: May be affected if blood sugar is too high or low; avoid driving if symptoms occur

Kidney Disease: Use with caution; dose adjustment may be required

Severe Kidney Disease: Not recommended

Liver Disease: Unsafe; should be avoided

Drug Interactions:

Inform your doctor about all medications, including herbal supplements

How to Use

Take as prescribed, with food

Swallow whole, do not crush or chew

Maintain consistent timing daily for optimal control

Summary

Sitapride-M 100/500 Tablet SR is a dual-action, sustained-release antidiabetic medicine that:

Controls high blood sugar levels in Type 2 Diabetes

Works through both insulin regulation and reduced glucose production

Helps prevent diabetes-related complications

Requires adherence to diet, exercise, and regular monitoring for best results

Patient Guidance:

Take at the same time every day

Regularly monitor blood sugar levels

Report persistent or severe side effects to your healthcare provider

Avoid alcohol and follow lifestyle recommendations