Product Description
Syntran 200 Capsule is a potent azole antifungal medicine used primarily to manage systemic and severe fungal infections. It is effective not only against internal infections but also for skin, nail, and mucosal fungal infections such as oral thrush, onychomycosis, and dermatophytosis.
In addition, Syntran 200 Capsule is often prescribed as a preventive measure for immunocompromised patients who are at higher risk of developing fungal infections. With proper medical supervision, it helps clear infections, prevents recurrence, and supports overall health.
Key Benefits
Treats severe systemic fungal infections like aspergillosis, candidiasis, and cryptococcosis
Manages skin and nail fungal infections, including onychomycosis and dermatophytosis
Effective for oral thrush and other mucosal Candida infections
Helps prevent fungal infections in immunocompromised individuals
Supports faster recovery and reduces risk of recurrent infections
Composition
Each Syntran 200 Capsule contains:
Itraconazole 200 mg – inhibits fungal cell membrane synthesis, leading to fungal cell death
How Syntran 200 Capsule Works
Syntran 200 Capsule acts by:
Blocking Ergosterol Synthesis: Itraconazole inhibits the enzyme lanosterol 14-alpha-demethylase, essential for fungal cell membrane formation.
Increasing Fungal Membrane Permeability: Disruption of the fungal membrane leads to leakage of cellular contents.
Stopping Infection Growth: Prevents fungal proliferation, effectively treating infections.
How to Use
Take the capsule orally, with or immediately after meals for optimal absorption.
Swallow whole; do not chew, crush, or break.
Follow the dosage and duration as prescribed by your doctor.
Complete the full course even if symptoms improve to prevent recurrence.
Possible Side Effects
Common side effects include:
Nausea, vomiting, or diarrhea
Headache and dizziness
Rash or itching
Fatigue and loss of appetite
Most side effects are temporary. Contact your doctor if symptoms persist or worsen.
Precautions & Warnings
Pregnancy & Breastfeeding: Consult your doctor before use.
Alcohol: Avoid, as it may increase liver toxicity and side effects.
Liver & Kidney: Use with caution in patients with liver or kidney issues.
Driving & Machinery: May cause dizziness or visual disturbances; avoid operating vehicles until effects are known.
Allergy: Do not use if allergic to itraconazole or capsule components.
Children & Elderly: Consult your doctor for age-appropriate guidance.
Drug Interactions
Antiarrhythmics: Risk of arrhythmias may increase
Statins: Higher risk of muscle-related side effects
Benzodiazepines: Sedation may be enhanced
Immunosuppressants & Anticoagulants: Increased effect leading to higher bleeding or immune suppression
Oral Hypoglycemics: Risk of low blood sugar may increase
Food Interactions: Avoid grapefruit and grapefruit juice during treatment.
Dosage Guidelines
Take exactly as prescribed by your doctor.
Missed Dose: Take as soon as remembered, unless it’s near the next scheduled dose.
Overdose: Seek immediate medical attention if more than the prescribed dose is taken.
Storage Instructions
Store below 30°C, away from light and moisture.
Keep out of reach of children.
Check the expiry date before use.
Diet & Lifestyle Recommendations
Maintain proper hygiene to prevent fungal spread.
Avoid grapefruit or grapefruit juice while on this medication.
Incorporate a healthy, balanced diet to support overall recovery.
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