Tazogud-4.5 GM

Tazogud 4.5 GM Injection is a combination antibiotic containing Piperacillin (4000 mg) and Tazobactam (500 mg). It is used to treat a wide range of bacterial infections by inhibiting bacterial cell wall synthesis and counteracting beta-lactamase enzymes that would otherwise degrade the antibiotic.

Uses

Tazogud 4.5 GM Injection is commonly prescribed for:

• Intra-abdominal infections (e.g., appendicitis, peritonitis)

• Skin and soft tissue infections (e.g., cellulitis, diabetic foot infections, cutaneous abscesses)

• Pelvic infections (e.g., postpartum endometritis, pelvic inflammatory disease)

• Lower respiratory tract infections (e.g., community-acquired pneumonia, ventilator-associated pneumonia)

• Bacterial sepsis

It is administered intravenously by a healthcare professional, with dosage and duration tailored to the patient’s age, weight, and severity of infection.

How It Works

• Piperacillin: A broad-spectrum penicillin antibiotic that disrupts bacterial cell wall synthesis, leading to bacterial cell death.

• Tazobactam: A beta-lactamase inhibitor that protects piperacillin from degradation by bacterial enzymes, enhancing its efficacy.

Common Side Effects

Most side effects are mild and may include:

• Diarrhea

• Nausea and vomiting

• Headache

• Insomnia

• Skin rash or itching

• Fever

• Injection site reactions (pain, swelling, redness)

Serious Side Effects

Seek immediate medical attention if you experience:

• Severe allergic reactions (e.g., difficulty breathing, swelling of face or throat)

• Severe skin reactions (e.g., blistering, peeling)

• Persistent or severe diarrhea

• Signs of liver or kidney issues (e.g., yellowing of skin or eyes, dark urine)

• Neurological symptoms (e.g., seizures, confusion, muscle twitching)

Precautions

• Allergy Alert: Avoid if allergic to penicillins, cephalosporins, or beta-lactam antibiotics.

• Renal Impairment: Use with caution in patients with kidney disease; dosage adjustments may be necessary.

• Pregnancy & Breastfeeding: Generally considered safe when prescribed by a doctor.

• Drug Interactions: May interact with other medications; inform your doctor of all drugs you are taking.

Administration

Tazogud 4.5 GM Injection is administered intravenously by a healthcare professional. Do not attempt to self-administer. Dosage and duration are determined based on the specific infection and patient factors.

Important Notes

• Complete the full course of treatment, even if you feel better, to prevent antibiotic resistance.

• Inform your doctor if you have a history of allergies, kidney or liver disease, or are pregnant or breastfeeding.

• Report any unusual or severe side effects promptly to your healthcare provider.

Always consult your healthcare provider for personalized medical advice and before starting any new medication.