Zanocin OD 400 mg Tablet – Once-Daily Antibiotic for Broad-Spectrum Bacterial Infections
Zanocin OD 400 mg Tablet is a powerful once-daily oral antibiotic designed to combat a variety of serious bacterial infections. With Ofloxacin as its active ingredient, this extended-release formulation delivers consistent antibacterial action throughout the day. It’s commonly prescribed for respiratory tract infections, urinary tract infections, sexually transmitted diseases, skin conditions, typhoid fever, and infectious diarrhoea.
As a broad-spectrum fluoroquinolone, Zanocin OD 400 mg is highly effective against numerous strains of Gram-negative, Gram-positive, and some anaerobic bacteria. It offers deep tissue penetration, making it especially useful in managing infections that are difficult to reach with standard treatments.
🦠 Indications & Therapeutic Uses
Zanocin OD 400 mg Tablet is prescribed for:
✅ Respiratory Tract Infections (e.g. pneumonia, bronchitis)
✅ Urinary Tract Infections (UTIs) and bladder infections
✅ Typhoid Fever and gastrointestinal bacterial infections
✅ Infectious Diarrhoea caused by bacterial pathogens
✅ Skin and Soft Tissue Infections
✅ Sexually Transmitted Infections (e.g. gonorrhoea, chlamydia)
✅ Bone and Joint Infections
✅ Prostate Infections (Prostatitis) in males
💊 How Zanocin OD 400 mg Tablet Works
Zanocin OD 400 mg contains Ofloxacin, an antibacterial agent that interferes with enzymes like DNA gyrase and topoisomerase IV, which are vital for bacterial DNA replication and repair. By blocking these enzymes, Ofloxacin halts bacterial growth and destroys the pathogens, effectively treating the infection and preventing its spread.
Its extended-release formulation allows once-daily dosing with sustained plasma levels, improving patient compliance and treatment outcomes.
🌟 Key Benefits
Once-daily dosing for enhanced convenience and better adherence
Broad-spectrum activity against both Gram-positive and Gram-negative bacteria
Deep tissue and fluid penetration, ideal for hard-to-treat infections
Suitable for various infection types, including respiratory, urinary, gastrointestinal, and sexual health
Clinically proven fluoroquinolone with fast symptom relief
📝 Dosage & Administration
Take Zanocin OD 400 mg Tablet once a day as prescribed
Preferably taken with food to enhance absorption and minimize stomach discomfort
Swallow whole with water—do not chew, crush, or break
Take it at the same time daily for optimal effectiveness
Avoid taking with milk, yogurt, or calcium-rich products, which may interfere with absorption
⚠️ Safety Information & Warnings
Before starting Zanocin OD 400 mg, inform your healthcare provider if you have or have had:
Kidney or liver disorders
Seizures or epilepsy
Heart rhythm disorders (e.g. QT prolongation)
Tendon problems or joint issues
Myasthenia gravis or other neuromuscular conditions
Any history of transplant (kidney, lung, or heart)
Allergies to quinolone antibiotics
Caution: Use in individuals over 60 years or those taking corticosteroids may increase the risk of tendon rupture or joint complications.
🤒 Common Side Effects
Most side effects are mild and resolve without intervention. However, consult a doctor if symptoms persist or worsen.
Nausea or vomiting
Diarrhoea or abdominal discomfort
Headache and dizziness
Changes in taste
Vaginal irritation or itching (in females)
Rash or mild skin reactions
Sleep disturbances
Seek immediate help if you experience allergic reactions such as swelling, severe rash, or difficulty breathing.
🧬 Drug & Food Interactions
Drug Interactions:
Avoid using with:
Bepridil
Ziprasidone
NSAIDs (can increase seizure risk)
Antiarrhythmics and other QT-prolonging drugs
Food Interactions:
Avoid dairy products around the time of dosing, as calcium may reduce drug absorption
Limit caffeine (tea, coffee, cola, chocolate) due to increased risk of nervousness and insomnia
Avoid alcohol to reduce dehydration and minimize nervous system side effects
🥗 Diet & Lifestyle Advice
Include probiotic-rich foods like yogurt, kefir, kimchi, and kombucha after your course to restore gut bacteria
Add fiber-rich foods such as whole grains, oats, and vegetables to aid digestion
Stay hydrated by drinking plenty of water
Avoid sunlight exposure during treatment to reduce the risk of photosensitivity
Refrain from high-intensity exercise during and shortly after treatment to avoid tendon strain
🧊 Storage Instructions
Store at room temperature between 10°C and 25°C
Keep away from heat, sunlight, and moisture
Ensure the tablet is out of reach of children
🚨 Overdose Management
In case of accidental overdose, symptoms may include:
Severe dizziness or confusion
Slurred speech
Numbness or facial swelling
Hot/cold flushes
Seek immediate medical attention if you suspect an overdose.
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