Cefrine Plus 375 Injection (Vial of 5 ml)

Cefrine Plus 375 Injection is a prescription antibiotic medicine widely used in hospitals and clinics for the treatment of bacterial infections affecting the respiratory tract, urinary tract, abdomen, skin, bones, joints, reproductive organs, and blood. It contains a combination of ceftriaxone and sulbactam, which work together to provide broad and effective antibacterial coverage. Ceftriaxone is a third-generation cephalosporin antibiotic that kills bacteria by damaging their cell wall, while sulbactam is a beta-lactamase inhibitor that prevents bacterial resistance, ensuring the antibiotic remains active. This injection is given under strict medical supervision by a doctor or nurse and is suitable for both adults and children, depending on the prescribed dose. By controlling infection at its source, Cefrine Plus 375 helps relieve fever, inflammation, pain, and discomfort while preventing the spread of infection. Completing the full prescribed treatment is essential to achieve complete recovery and prevent antibiotic resistance.

Benefits

• Provides dual antibacterial action with ceftriaxone and sulbactam

• Effective in treating respiratory infections such as pneumonia and bronchitis

• Useful in urinary tract and bladder infections

• Controls bloodstream infections like septicemia

• Helps treat intra-abdominal infections

• Works against skin and soft tissue infections

• Useful in bone and joint infections

• Provides protection in gynecological and reproductive tract infections

• Prevents surgical site infections when given before surgery

• Reduces fever and associated discomfort caused by infection

• Helps in both community-acquired and hospital-acquired infections

• Provides broad coverage against gram-positive and gram-negative bacteria

• Faster recovery compared to single antibiotic therapy

• Reduces recurrence and complications from bacterial illness

• Suitable for pediatric and adult use under medical guidance

Possible Side Effects

• Pain, redness, or swelling at the injection site

• Mild diarrhea or loose stools

• Stomach upset or nausea

• Headache or dizziness

• Skin rash or itching in some patients

• Fever or chills occasionally

• Rare allergic reaction with swelling or breathing difficulty

• Abnormal liver or kidney function in prolonged use

How To Use

• Administered only by a healthcare professional into a vein or muscle

• Dosage and frequency depend on the type and severity of infection

• Should be given at fixed intervals for best results

• Do not self-inject at home unless specifically advised

• Complete the full course even if symptoms improve early

• Store vials as per manufacturer’s instructions in a cool and dry place

How It Works

• Ceftriaxone destroys bacteria by weakening their cell wall

• Sulbactam prevents bacteria from neutralizing ceftriaxone

• The combination ensures stronger and longer-lasting antibacterial action

• Clears bacterial infection and reduces recurrence risk

• Provides relief from fever, pain, and inflammation

What To Avoid

• Avoid stopping treatment midway without doctor’s advice

• Avoid self-administration without medical guidance

• Avoid alcohol during the treatment period

• Avoid skipping scheduled doses in hospital care

• Avoid use in viral or fungal infections

• Avoid combining with other antibiotics unless prescribed

• Avoid using expired or improperly stored vials

• Avoid overdosing beyond the prescribed limit

• Avoid ignoring severe diarrhea or rash after injection

• Avoid reusing leftover vials for future illness

Safety Advice

• Use strictly under medical supervision in hospital or clinic

• Inform doctor about any kidney or liver disease before starting

• Pregnant or breastfeeding women should use only after medical consultation

• Patients taking blood thinners or heart medicines should inform their doctor

• Regular monitoring may be needed for long-term therapy

• Ensure proper hydration during treatment

• Report any unusual reactions like rash, swelling, or breathing issues immediately

• Keep vials out of children’s reach

• Do not use beyond recommended duration

• Follow up with doctor if symptoms persist after treatment

Precautions

• Not suitable for patients allergic to cephalosporins, penicillins, or beta-lactam antibiotics

• Caution required in patients with seizure disorders or brain conditions

• Inform doctor if history of severe diarrhea with antibiotics exists

• Dose adjustment may be required in patients with kidney or liver impairment

• Stop immediately and seek help if severe allergic reaction occurs

• Long-term or unnecessary use may cause resistance

• Sterile technique must always be followed to avoid secondary infection

• Not to be used for viral illnesses like flu or common cold

• Do not share injection with others

• Always complete the course as prescribed