Glucreta M 10/500 Tablet ER – Product Overview
Glucreta M 10/500 Tablet ER is an extended-release combination medicine used to manage type 2 diabetes mellitus. It combines Dapagliflozin and Metformin, which work together to lower blood sugar levels and reduce the risk of serious complications such as kidney damage, vision impairment, nerve disorders, and heart disease.
This medicine should be used as part of a comprehensive treatment program including healthy diet, regular exercise, and weight management.
Uses
Treatment and control of Type 2 Diabetes Mellitus
Reduces the risk of cardiovascular complications in diabetic patients with heart disease
Benefits
Dual Mechanism of Action
Dapagliflozin removes excess glucose through urine.
Metformin reduces glucose production in the liver, slows glucose absorption from the intestines, and increases insulin sensitivity.
Complication Prevention
Consistent blood glucose control lowers the risk of kidney damage, blindness, nerve problems, cardiovascular events, and other diabetes-related complications.
Improved Quality of Life
Regular use with diet and exercise supports overall metabolic health and helps maintain normal daily activities.
How It Works
Dapagliflozin: A sodium-glucose co-transporter 2 (SGLT2) inhibitor that removes excess glucose from the body via urine.
Metformin: A biguanide that decreases glucose production in the liver, slows intestinal absorption, and improves insulin sensitivity.
Together, they provide better control of fasting and post-meal blood sugar levels.
Recommended Dosage
Take as prescribed by your doctor.
Swallow the tablet whole; do not chew, crush, or break.
Take with food to reduce stomach upset.
Take at the same time every day to maintain consistent blood sugar levels.
Common Side Effects
Most side effects are mild and usually disappear as your body adjusts. Report persistent or severe symptoms to your doctor.
Nausea, vomiting, diarrhea
Genital fungal infections
Nasopharyngitis (throat and nasal inflammation)
Urinary tract infections, polyuria
Flatulence, skin rash, taste changes
Difficulty in urination, dizziness, tremors
Back pain
Increased hematocrit, decreased creatinine clearance
Dyslipidemia
Hypoglycemia (low blood sugar)
Safety Advice
Alcohol: Unsafe; may increase risk of side effects.
Pregnancy: Consult your doctor; may be unsafe. Discontinue if pregnancy occurs.
Breastfeeding: Consult your doctor; may be unsafe.
Driving: Exercise caution if blood sugar is too low or high. Avoid driving if affected.
Kidney: Use with caution; dose adjustment may be required. Avoid in severe kidney disease.
Liver: Use with caution; dose adjustment may be required. Avoid in severe liver disease.
Patient Guidance
Do not stop medication without consulting your doctor.
Maintain a healthy diet and exercise routine.
Stay hydrated and monitor blood sugar regularly.
Inform your doctor of any kidney, liver, or urinary issues, or if you are on diuretics.
Summary:
Glucreta M 10/500 Tablet ER is an effective treatment for type 2 diabetes, combining Dapagliflozin and Metformin to manage blood sugar levels and reduce complications. Regular use along with lifestyle measures helps maintain long-term health and quality of life.
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