Sitanorm-DM 500 Tablet

Sitanorm-DM 500 Tablet – Comprehensive Overview
Product Introduction

Sitanorm-DM 500 Tablet is a triple-combination oral antidiabetic medicine designed for the management of Type 2 Diabetes Mellitus (T2DM) in adults. Type 2 diabetes is a condition where the body either does not produce enough insulin or cannot effectively use the insulin produced, resulting in elevated blood sugar levels (hyperglycemia).

Sitanorm-DM 500 Tablet works in combination with a healthy diet, regular exercise, and lifestyle modifications to improve glycemic control, reduce complications, and support long-term health in patients with diabetes.

Composition

Dapagliflozin 10 mg – SGLT2 inhibitor

Sitagliptin 100 mg – DPP-4 inhibitor

Metformin 500 mg – Biguanide

Form: Oral Tablet
Category: Antidiabetic combination therapy

Mechanism of Action

Sitanorm-DM 500 Tablet offers multi-targeted glycemic control through three complementary mechanisms:

Dapagliflozin: Promotes urinary glucose excretion, lowering blood sugar independent of insulin.

Sitagliptin: Increases the levels of incretins, which stimulate insulin release and suppress glucagon secretion, reducing hepatic glucose production.

Metformin: Reduces glucose production in the liver, delays intestinal glucose absorption, and increases peripheral insulin sensitivity.

The combined effect of these three drugs ensures better overall control of fasting and postprandial blood glucose levels compared to single or dual therapy.

Indications / Uses

Primary Use: Management of Type 2 Diabetes Mellitus in adults.

Secondary Benefits:

Helps reduce the risk of diabetes-related complications, including kidney, eye, and nerve damage.

Supports cardiovascular health by improving vascular function and reducing albuminuria.

Assists in weight and metabolic control, particularly in overweight or obese diabetic patients.

Promotes glycemic stability and lowers HbA1c levels.

Dosage and Administration

Route: Oral

Dose: As prescribed by your doctor

Timing: Take at the same time each day for consistent control

Food: Recommended to take with meals to reduce gastrointestinal side effects

Important Instructions:

Swallow the tablet whole; do not chew, crush, or split.

Do not stop medication abruptly without consulting your doctor.

Combine therapy with a healthy diet and regular exercise.

Side Effects

Most side effects are mild and resolve over time. Contact your doctor if they persist or worsen.

Common Side Effects:

Vomiting, nausea, abdominal pain

Headache

Stomach upset

Loose or watery stools

Gas or flatulence

Upper respiratory infections (common cold, nasopharyngitis)

Genital fungal infections (in women)

Low blood sugar (hypoglycemia), especially when combined with other antidiabetic medications

Precautions:

Drink plenty of fluids to prevent dehydration.

Maintain good hygiene to reduce risk of fungal infections.

Warnings and Precautions

Allergy: Avoid if allergic to any of the components.

Liver or Kidney Disease: Not recommended in severe liver or kidney impairment. Dose adjustment may be needed in mild/moderate cases.

Pregnancy & Breastfeeding: Consult your doctor before use.

Children: Not recommended under 18 years of age.

Alcohol: Avoid consumption, as it may increase the risk of hypoglycemia or lactic acidosis.

Overdose: Signs may include dizziness, nausea, vomiting, stomach pain, or low blood sugar. Seek immediate medical attention if suspected.

Drug Interactions:

Inform your doctor about all medications, including supplements and herbal remedies, to avoid interactions.

How It Works

Sitanorm-DM 500 Tablet combines three antidiabetic agents:

Dapagliflozin – Promotes glucose excretion via urine.

Sitagliptin – Enhances insulin secretion and reduces liver glucose production.

Metformin – Reduces hepatic glucose output, delays intestinal absorption, and improves insulin sensitivity.

Together, these mechanisms provide comprehensive blood sugar management for patients not controlled by single or dual therapy.

Storage Instructions

Store in a cool, dry place away from direct sunlight.

Maintain room temperature between 10–25°C or below 30°C.

Keep out of reach of children.

Summary

Sitanorm-DM 500 Tablet is a triple-action antidiabetic therapy that effectively:

Controls high blood sugar levels in Type 2 diabetes

Reduces complications like kidney, eye, and nerve damage

Supports cardiovascular and metabolic health

Enhances glycemic stability and lowers HbA1c

Key Points for Patients:

Take regularly at the same time daily.

Follow your diet and exercise plan.

Monitor blood sugar and watch for symptoms of hypoglycemia.

Report persistent side effects to your healthcare provider.