Xone ES 1.5 gm

About Xone ES 1.5 gm Powder for Solution Injection

Xone ES 1.5 gm Powder for Solution Injection is an antibiotic used to manage serious bacterial infections, particularly those caused by gram-negative organisms. These infections occur when harmful bacteria multiply in the body, leading to various health complications.

This medicine contains three active components:

• Ceftriaxone – a third-generation cephalosporin antibiotic that destroys bacteria by damaging their protective cell wall.

• Sulbactam – a beta-lactamase inhibitor that prevents bacterial resistance and improves the action of ceftriaxone.

• Disodium Edetate – works as an antibiotic resistance breaker, further enhancing the effectiveness of the treatment.

Together, these agents provide broad and potent antibacterial activity, especially in difficult-to-treat or resistant infections.

Uses of Xone ES 1.5 gm Injection

Xone ES is prescribed for the treatment of severe bacterial infections, including:

• Respiratory tract infections such as pneumonia and bronchitis

• Complicated urinary tract infections (including resistant strains)

• Skin and soft tissue infections like cellulitis, abscesses, and wound infections

• Bone and joint infections such as osteomyelitis and septic arthritis

• Other life-threatening infections caused by resistant bacteria

Benefits

• Broad coverage against gram-negative and resistant bacteria

• Combines antibiotic and resistance-breaking agents for stronger efficacy

• Effective in serious infections where other antibiotics may fail

Possible Side Effects

Most side effects are mild and temporary, but medical advice may be required if they persist. Common reactions include:

• Pain, redness, or swelling at the injection site

• Diarrhea or loose stools

• Nausea or abdominal discomfort

• Rashes or skin irritation

• Temporary changes in blood cell counts (white blood cells, platelets, eosinophils)

Seek immediate help if allergic symptoms (swelling, severe rash, breathing difficulty) occur.

How It Works

• Ceftriaxone disrupts bacterial cell wall formation, leading to cell death.

• Sulbactam blocks bacterial enzymes that cause drug resistance, making ceftriaxone more effective.

• Disodium Edetate further enhances antibacterial activity by reducing resistance.

This triple mechanism ensures stronger and longer-lasting infection control.

Directions for Use

• The injection is administered only by a healthcare professional.

• Do not self-administer.

• Dosage and duration are decided by the doctor based on infection type and patient condition.

Storage

• Store in a cool, dry place below 30°C, away from sunlight.

• Keep out of reach of children.

Warnings & Precautions

• Inform your doctor if you are allergic to cephalosporins, penicillins, or any component of this medicine.

• Use during pregnancy only if clearly prescribed by a doctor.

• Breastfeeding may need to be paused while on treatment.

• Avoid alcohol consumption during the treatment.

• Caution is advised in patients with severe liver problems, kidney issues, or history of intestinal infections (such as Clostridium difficile).

• Complete the full course as prescribed to prevent recurrence and resistance.

Lifestyle & Dietary Advice

• Include probiotics or fermented foods (yoghurt, kimchi, sauerkraut) after completing the antibiotic course to restore healthy gut bacteria.

• Eat fibre-rich foods like whole grains, fruits, and vegetables to support gut health.

• Drink plenty of water and rest well to aid recovery.

• Avoid alcohol as it may interfere with treatment and cause dehydration.